Danuta Szczesna-Cordary, PhD Email: email@example.com Myosin Light Chain Mutant Induced Cardiomyopathies The major theme of my research regards myosin and troponin-mediated cellular events that result in sarcomere shortening and muscle contraction studied at the molecular, myofilament and organ levels. Our recent research interests concentrate on the molecular and genetic causes of cardiomyopathy with a special […]
Congratulations to Yoel H. Sitbon, a graduate student in the lab of Dr. Szczesna-Cordary for having his recent article, “Ablation of the N-terminus of cardiac essential light chain promotes the super-relaxed state of myosin and counteracts hypercontractility in hypertrophic cardiomyopathy mutant mice” accepted for publication in The FEBS Journal. The article explores a new role for the N-terminus of cardiac ELC […]
Congratulations, Sunil Yadav, on successfully defending your dissertation and becoming Dr. Sunil Yadav!
On December 9, 2019, Sunil Yadav successfully defended his dissertation, titled “Exploring Myosin RLC Phosphorylation as a Potential Novel Therapeutic Target for Hypertrophic Cardiomyopathy” to earn his doctoral degree! Congrats, Sunil! Serving as his committee members were Drs. Claudia Rodrigues (Chair), Fangliang Zhang, Arun Malhotra, and Peter Buchwald. Dr. Audrey Chang, an Assistant Professor at UT Southwestern Medical Center, serves as […]
Amber is a master student at the University of Miami, Miller School of Medicine and her projects in the DSC lab will include ATP chase experiments on ELC/RLC fibers from HCM, RCM and DCM mice models. Welcome to the lab Amber, hope you will enjoy your time here and will learn a lot!
Joshua is a master student at the University of Miami, Miller School of Medicine and his projects in the DSC lab will include ATP chase experiments on ELC/RLC fibers from HCM, RCM and DCM mice models. Welcome Josh!
From left to right: Jingsheng Liang, Katarzyna Kazmierczak, Sunil Yadav, Danuta Szczesna-Cordary, Yoel Sitbon, Amber Jackson, Joshua Wagner
Yoel passed his first progress meeting in August and his committee members are happy with his experimental progress and are excited to see what will be the next findings! Keep up, Yoel!
Sunil Yadav has recently been accepted in a summer internship program at MyoKardia, Inc., a San Francisco based precision cardiovascular medicine company, working on targeted therapies for heritable Cardiomyopathies. Their line of research greatly overlaps with the basic science research Sunil is involved in as a graduate student, and he believes this internship opportunity will help him further explore leading […]
Please welcome Melanie Veerasammy, a junior majoring in Biology and minoring in Chemistry and Public Health at the University of Miami! She will be volunteering in the lab every day for the summer 2019.
Please welcome Melanie Veerasammy, a junior majoring in Biology and minoring in Chemistry and Public Health at the University of Miami! She will be volunteering in the lab every day for the summer 2019. She has many shadowing and leadership experience and wishes to pursue an MD-PhD degree following her bachelor’s degree. She will be working […]
We are very pleased to present our newest publications: Therapeutic potential of AAV9-S15D-RLC gene delivery in humanized MYL2 mouse model of HCM Hereditary heart disease: pathophysiology, clinical presentation, and animal models of HCM, RCM, and DCM associated with mutations in cardiac myosin light chains Phosphomimetic-mediated in vitro rescue of hypertrophic cardiomyopathy linked to R58Q mutation […]