Danuta Szczesna-Cordary, PhD Email: email@example.com Myosin Light Chain Mutant Induced Cardiomyopathies The major theme of my research regards myosin and troponin-mediated cellular events that result in sarcomere shortening and muscle contraction studied at the molecular, myofilament and organ levels. Our recent research interests concentrate on the molecular and genetic causes of cardiomyopathy with a special […]
Katarzyna Kazmierczak, PhD Email: firstname.lastname@example.org Development of physiological versus pathological cardiac hypertrophy in animal models of cardiomyopathy expressing mutations in MYL2 and MYL3.
Jingsheng Liang, MD Email: email@example.com Studies of the effect of genetic mutations in MYL2 and MYL3 on the skinned fiber mechanics (force-pCa, maximal tension, passive tension).
Yoel’s research will focus on Essential Light Chain (ELC) mutations that lead to cardiomyopathy via changes in ELC structure, and the ability of myosin to effectively interact with actin, ultimately leading to dysregulated cardiac muscle contraction. He will also be studying how mutations in ELC regulate the Super-Relaxed State of myosin and will additionally look […]
Newest addition to the lab, Michelle , a master student at the University of Miami Miller School of Medicine. Her projects will include ATP chase experiments, data analysis and reconstituted fiber experiments in RLC animals.
The DSC lab would like to welcome AJ, a master student at the University of Miami Miller School of Medicine. His projects will include ATP chase experiments and data analysis in ELC animals!
Jason Breithaupt, medical student at the Miller School of Medicine. He will take part in various projects in the lab including PV and echocardiography data analysis of RLC mutant mice.